As a lab, we are committed to building a diverse and inclusive community, and believe that diversity fosters creative, paradigm shifting science.
The Plavicki Lab is a multidisciplinary group asking questions about basic developmental process as well as examining how our health is shaped by our complex chemical environments.
The Plavicki lab is located in the Laboratories for Molecular Medicine at 70 Ship in the heart of the Jewelry District. We are equipped with a Zeiss LSM 880 confocal microscope with Airyscan Fast, modified Noldus DanioVision units with LEDs for optogenetic manipulations, our own fish facility, and so much more!
The Plavicki Lab was started with the support of NIH K99/R00 and is currently funded by a Outstanding New Environmental Scientist Award (R01) from NIEHS. Current lab members are supported by prestigious fellowships including the NSF GRFP, NIH F31, and NIH F32.
Central Nervous
System Development
The Plavicki lab is interested in understanding the basic science behind how the brain develops. Additionally we seek to elucidate how early-life exposures to environmental contaminants affect brain development and behavioral endpoints.
Cardiovascular Development
The Plavicki lab is interested in understanding how the heart and the great vessels, the vessels that bring blood to and from the heart, develop. We use an array of microscopy, behavior, and cardiac output tools to determine the pathways of cardiac development.
Toxicology
The Plavicki lab is interested in understanding how toxicant exposures during early life can affect the development of critical organs. We are primarily interested in the impact of toxicants on cardiac and central nervous system development.
Current research support
5R01ESO030109-02NIH/NIEHS
02/2020-02/2025
Toxicant induced dysregulation of parvalbumin interneuron development and function.
Role: Principal Investigator
2P20GM103652
NIH/NIGMS
02/2018-02/2023
Sox9b function in cardiomyocyte and great vessel development
Role: Project Leader
NSF-MRI
MRI: Acquisition of a High-Resolution Liquid Chromatography-Mass Spectrometer
for Environmental Monitoring and Metabolomics Research and Training
Role: CO-I
Post-Doctoral Fellowship support
NIH NIEHS F32Michelle Kossack
8/2021 - 7/2022
Student Fellowship support
NSF-GRFPLayra Cintrón-Rivera
09/2020 - 09/2023
NIH NHLBI F31
Shannon Martin
01/2021 - 12/2024
completed research support
K99ES023848NIH/NIEHS
09/2014-09/2016
Ahr2 activation and sox9b function in forebrain and cerebral vascular development
Role: Principal Investigator
4R00ES023848
NIH/NIEHS
02/2017-02/2020
Ahr2 activation and sox9b function in forebrain and cerebral vascular development
Role: Principal Investigator
Superfund Research Program Seed Funds
06/2017-06/2019
